Urgent Radiotracer Shortage Threatens Cardiac Amyloidosis Diagnosis, Plus Cardiometabolic Updates

Supply issues with key radiotracers for diagnosing cardiac amyloidosis are expected after this month, according to the American Society of Nuclear Cardiology. Large cardiology societies drew attention to environmental stressors on cardiovascular health. (Journal of the American College of Cardiology) Cardiologists panned the red meat- and saturated fat-heavy diet endorsed in the new 2025-2030 Dietary Guidelines for Americans. (CNN) Early success was reported for the innovative Cardiometabolic Fellowship at the University of Missouri-Kansas City. (Circulation: Population Health and Outcomes) Blood pressure (BP) tracked over time, from birth to elementary school age, according to a cohort study. (JAMA Network Open) Scientists showed the importance of beige adipocytes in BP regulation and warding off the harmful enzyme QSOX1. (Science) The Farapulse pulsed field ablation (PFA) platform is now expanded with FDA clearance of Boston Scientific's Farapoint focal PFA catheter. (MedTech Dive) Imricor's Vision-MR diagnostic catheter was FDA cleared for electrophysiological mapping under MRI guidance. For COVID‐19 patients on direct oral anticoagulants for atrial fibrillation, it made no difference on short-term survival whether they were given concomitant nirmatrelvir/ritonavir (Paxlovid) or an antiviral like remdesivir (Veklury), based on a retrospective analysis from Hong Kong. (Journal of the American Heart Association) Just 5 minutes more of daily physical activity could be tied to a reduced mortality risk, an individual-level meta-analysis found. (The Lancet) Increased risk for cardiovascular events was associated with exercise systolic blood pressure relative to fitness, according to a large Australian study. (European Heart Journal) Bristol Myers Squibb announced mavacamten's (Camzyos) win in the phase III SCOUT-HCM trial in teenagers with symptomatic obstructive hypertrophic cardiomyopathy. Coexisting hypertension, prediabetes, and subclinical myocardial injury or stress were associated with incident heart failure. (JAMA Cardiology) A novel gut- and liver-restricted LXR inverse agonist showed promise for triglyceride reduction in a phase I study. (Nature Medicine)