Space & Astronomy
4 min read
Nanorana parkeri: How High-Altitude Frogs Survive on the Xizang Plateau
geneonline.com
January 20, 2026•2 days ago

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The high-altitude frog *Nanorana parkeri* on the Xizang Plateau exhibits notable plasma metabolite and lung gene adaptations for survival. Researchers found significant shifts in metabolic profiles and gene expressions related to oxygen transport, energy, and stress response. These changes indicate unique mechanisms developed by the species to cope with low-oxygen, high-elevation environments, offering insights into amphibian adaptation.
High-Altitude Frog Nanorana parkeri Shows Plasma Metabolite and Lung Gene Adaptations for Survival on Xizang Plateau
Researchers have identified significant changes in plasma metabolite profiles and lung gene expression in the high-altitude frog species *Nanorana parkeri*, native to the Xizang Plateau. The study, conducted in one of the most extreme environments on Earth, highlights how elevation influences biological processes in this amphibian species. The findings provide new insights into how these frogs adapt to their challenging habitat.
The research focused on analyzing plasma metabolites and lung gene activity to understand physiological adaptations to high-altitude conditions. Scientists observed notable shifts in metabolite levels and specific gene expressions linked to oxygen transport, energy metabolism, and stress response. These changes suggest that *Nanorana parkeri* has developed unique mechanisms to survive in low-oxygen environments at high elevations. The study sheds light on the broader impacts of altitude on amphibian biology and adaptation strategies.
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Date: January 20, 2026
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