Thursday, January 22, 2026
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Karolinska Institute Study: Functional Prefrontal Cortex Boundaries Differ

geneonline.com
January 20, 20262 days ago
Karolinska Institutet Study Finds Functional Boundaries in Mouse Prefrontal Cortex Differ from Structural Maps

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A Karolinska Institutet study reveals functional boundaries in mouse prefrontal cortex differ from traditional structural maps. For over a century, brain regions were defined by microscopic structure, but this research indicates these divisions don't accurately reflect brain activity. The findings challenge existing brain mapping assumptions and suggest new approaches are needed for understanding brain function and organization.

A recent study conducted by researchers at Karolinska Institutet challenges long-standing assumptions about brain mapping. For over a century, scientists have divided the brain into regions based on structural differences observed under a microscope. However, findings from this new research, published in *Nature Neuroscience*, suggest that these anatomical divisions may not accurately reflect how the brain functions. The study focused on the prefrontal cortex of mice and revealed discrepancies between traditional structural maps and actual brain activity patterns. The research team analyzed brain activity in mice to determine whether functional boundaries align with the structural regions defined by microscopic examination. Their findings indicate that many functional processes do not correspond neatly to these established anatomical divisions. This raises questions about the accuracy of traditional methods used to map the brain and suggests that alternative approaches may be necessary to better understand its workings. The study provides new insights into how scientists might approach future research on brain function and organization. Newsflash | Powered by GeneOnline AI Source: GO-AI-ne1 For any suggestion and feedback, please contact us. Date: January 20, 2026

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    Brain Function Study: Prefrontal Cortex Boundaries