Health & Fitness
4 min read
Fluoroquinolone Antibiotics Found to Alter Macrophage Bacterial-Killing Functions
geneonline.com
January 20, 2026•2 days ago

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A study by Lancaster University researchers found that fluoroquinolone antibiotics can alter the bacterial-killing functions of macrophages, a type of immune cell. This suggests these antibiotics may impact the immune system beyond their direct antibacterial action. The findings highlight a significant interaction between fluoroquinolones and macrophages, warranting further investigation into their effects on immune responses.
Study Finds Fluoroquinolone Antibiotics Can Alter Macrophage Bacterial-Killing Functions
A recent study conducted by researchers at Lancaster University has identified that fluoroquinolones, a class of antibiotics, can influence the bacterial killing capability of macrophages, a type of immune cell. The findings suggest that these antibiotics may have an impact on the immune system beyond their primary function of targeting bacterial infections.
Macrophages play a critical role in the body’s defense mechanisms by engulfing and destroying harmful pathogens. According to the research, fluoroquinolones appear to directly alter how these cells perform their bacterial-killing functions. The study highlights this interaction between fluoroquinolones and macrophages as a potential area for further investigation into how antibiotics might affect immune responses. Researchers did not provide additional details on whether this effect is beneficial or detrimental but noted its significance in understanding antibiotic interactions with immune cells.
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Date: January 20, 2026
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