Dietary Fat Ratio Alters Metabolism Independently of Body Weight, New Study Finds

Study Finds Dietary Carbohydrate-to-Fat Ratio Alters Metabolism Independently of Body Weight Changes A recent study published in *Nature Communications* reveals that the ratio of dietary carbohydrates to fats significantly impacts human metabolism, regardless of changes in body weight. Researchers, including Angelidi, Bartell, and Huang, conducted a five-month randomized controlled feeding trial to examine how varying macronutrient ratios affect metabolic processes. The findings highlight that dietary composition alone can alter metabolites in the body without requiring weight loss or gain. The study involved a carefully controlled diet intervention where participants consumed meals with differing carbohydrate-to-fat ratios over an extended period. Researchers monitored metabolic changes through blood samples and other biomarkers to assess how these dietary adjustments influenced metabolite levels. The results suggest that specific macronutrient balances can independently modify metabolic pathways, shedding light on potential implications for personalized nutrition strategies and metabolic health research. Newsflash | Powered by GeneOnline AI Source: GO-AI-ne1 For any suggestion and feedback, please contact us. Date: January 19, 2026